GHK Cu

Overview

Support for tissue dynamics mediated by a peptide metal complex.

Mechanism of action

A solid product description should emphasize that GHK Cu is one of the more extensively studied “cosmetic adjacent” peptides on your list, with published reviews summarizing molecular and gene level effects—while still avoiding claims that it cures medical skin diseases unless regulated as a drug in your market.

For non experts: GHK Cu is often called a “copper peptide” because copper is an essential cofactor in many biological repair and enzymatic processes. In skincare science, GHK Cu is typically discussed in the context of skin appearance, firmness, and repair signaling, though the strength of evidence can vary by formulation and endpoint.

GHK Cu is a copper(II) binding tripeptide complex (Gly His Lys + copper) that occurs naturally in the human body and has been widely studied in skin and connective tissue biology. The peptide is notable for its reported ability to influence processes central to tissue remodeling, including collagen and glycosaminoglycan dynamics, metalloproteinase (MMP) regulation, antioxidant signaling, and wound healing related gene expression patterns.

Authenticity

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